Abstract: For asymmetric facade shape masonry wall, there is a failure mode of inclined cracks along the nodes of the wall limbs.In this failure mode, the main crack starts from the intersection of the wall between the windows and the wall below the windows, and gradually develops and expands in an oblique downward direction.The failure concept of oblique crack along the node of asymmetric masonry wall was defined, and the generation mechanism of this failure mode was analyzed.Combined with experimental research and finite element simulation, the calculation method of horizontal bearing capacity of the wall under the failure mode of oblique cracks along the joints of the wall limbs was proposed.The actual test data of masonry walls were compared with the theoretical calculation results of bearing capacity.The research shows that the calculation method of horizontal bearing capacity proposed has a very good correspondence with the actual failure mode of asymmetric masonry wall, and has a clearer physical significance compared with the inclined crack failure of the wall between windows.For the asymmetric facade masonry wall, in addition to checking the shear bearing capacity of the wall between windows according to the existing calculation method, the supplementary checking calculation should be carried out according to the inclined crack failure mode along the node, and the smaller value is taken as the horizontal bearing capacity of the wall limb, and then the seismic design is carried out, which is helpful to improve the seismic safety reserve of this kind of masonry wall.